I would only use better-quality pages, and I would be inclined to pick one company and stick with them. For me, that choice was Vario. I do occasionally pick up other makers' pages, for general storage purposes.
Most of my pages are the standard Varios, but I do have some Vario Plus pages. The Plus pages are very nice. Very heavy and stiff. You pay a penalty in binder capacity and initial cost with the Plus pages, so they would not be practical for most worldwide collectors.
I store my binders vertically, and I'm generally careful with turning pages. I don't get much stamp movement on the pages, but I can't say it is none. I just grabbed a thin binder with about 20 pages (40 sides), and as I flipped through it, I saw fewer than ten stamps that could have used an adjustment. Only one was significantly shifted. If I bring some pages to the local philatelic society, and a number of different people are flipping through them, there is definitely some shifting by the end of the night. Knock on wood, nothing has yet to escape.
For me, the two biggest issues to work through are picking pocket counts and making annotations. I mostly limit myself to pre-1940, so there is quite a bit of uniformity in stamp sizes, but you'll scratch your head when you run across something like this one, from Gibraltar:

as he and his neighbors will dictate using a page with only a few pockets; which means that the other side of the page will have the same number of pockets, too. It can sort of gum up the works. I can't bring myself to turn stamps on their sides (except in the storage binders) and I don't let stamps stick up above the tops of the pockets.