I
inherited a collection my great-grandfather started. It has contributions, by at least six people, over four generations, each with their own focus of collecting. 'Gaps' should be my ID.
Rhett posted the opinion he'd heard that "a collection is defined more by what it doesn't contain than by what it does".
Our US classic part of the collection doesn't contain the first almost forty years of stamps. It begins in 1887. It doesn't contain every stamp in a series.
I did rough drafts, before deciding whether to create my own pages, or buy albums. I could have pages that look like the one below, and put the rest on stock pages. The bulk of the collection would be in a stock book.

A community member here, suggested I put them
all on pages in the 'main album'. While pondering how in the world I was going to do that, I 'chewed over the food for thought' what the collection didn't contain, served up. I came to the conclusion the collection was begun the year my great-grandfather, who started it, was born, and he collected for cancels and postmarks, not individual stamps.
The resulting draft(s) turned out like this first page of the 'Targets' section.

I liked it better, so I created pages that focus on the postmarks and cancels, not the missing stamps. There are sections of pen, manuscript, cork, handstamp, machine cancels, etc. They are in the binders in chronological order of their use. The blank spaces on the page, I can fill in with information about the cancel, or about a particular stamp that might stand out, in the group. I can also arrange them, so the pages lay flat. I like the flexibility creating my own pages gives, and the end results, I'm seeing.
I also like the fact, instead of one binder, filled with the dreaded, hated gaps, and empty pages, with at least two stockbooks, I now have two binders, each page filled, and one stockbook mostly empty.
The missing #214 on the page above doesn't bother me and I'm not inclined to point it out, by putting a filler, or sample in it's place. If I do get one, and it has a target cancel, since I made the page, I can always rearrange it, to fit it in. Not to mention, I might have one, but with a different cancel. You probably won't notice, until you reach the end of the classics section, there isn't a #214 in the collection.
You mentioned topical as an option. If what your collection is missing defines it as a topical one, or that is the route you
want to go, then go for it.
A quote I found helpful, and hope it does to you, and others reading.. "It's your collection. Make it how you want it, so you can enjoy it". Good luck with whatever option you decide. I hope you find a way to arrange it so the dreaded, hated gaps don't detract from your enjoyment.