A little more information would be helpful in determining how to proceed.
1. A bunch of loose stamps or stamps in albums?
2. What inclusive years to these stamps represent ... 1860-1970s for example?
3. What countries?
4. Used or unused, or both?
5. 100 stamps or 10,000 stamps or some number in between
You can look in any number of on-line stamp catalogs to get an idea of "catalog" value, but actual sales value is typically some discount from catalog value... say 40-60% depending on the stamp, its condition, new or used, etc.
If it is a large collection, you might want to ship it off to a dealer for an appraisal of value. I have never used a dealer for that purpose, but I have heard good things about
http://www.stampbuyer-wisconsin.com/ Bill Robinson Auctions, Green Bay WI