Interesting discussion. I've been thinking about this a lot since inheriting my collection last fall. At first I saw it as a potential investment, but now view it as a hobby. And unlike most hobbies, one that will actually have some (limited) value for my children when I pass away. (I also
inherited some coins, but haven't had the courage to dive into that yet :))
So I'm having it appraised and then will write down some instructions on how to dispose of it, so my kids can realize some value if they choose to sell it. Of course, I hope one of them continue the collection, since it would be the 4th generation of stamp collecting in our family, with the same core collection, but that's up to them.
Until then, my plan is to build the collection at a steady pace, buying high-quality stamps in the areas that the collection already covers and interest me (WW classic, Canada, Germany). And also focus it by selling the areas that are weak/I have little interest in (US, WW modern).