The H. K. Mulford Company in Philadelphia, Pennsylvania operated from the late 1880s until they were acquired by the Sharp and Dohme Corporation in late 1929. They made a variety of products containing narcotics.
This is their more commonly seen cancellation:

This cancel at first seems to read "H. K. Co."

However, when other stamps with the same cancel were found, it was clear that the H. K. Mulford Company also used a much, much larger cancel than their more common cancel.


It was almost as if someone was over-compensating for their first, tiny cancel, that somebody in upper management had complained was too hard to read, by making a ridiculously large cancel.
Or maybe it was the other way around, and the guy that made the first huge cancel was told to make it smaller, so he shrunk it way down to a teeny, tiny size?
Jim