Clark, as always, thank you for your knowledge and willingness to share.
Regarding the perfs individually, they look on close inspection to have some authentic traits (not perfectly round, fibers present on ends). The rows line up across the stamps. The abnormal spacing exists between perfs 5 & 6 from the top--spacing is smaller than the rest. But, that space abnormality is consistent in each row.
How about a loose perforator pin causing the out-of-position hole? That would explain the row to row consistency. Otherwise, someone took a genuine 452 coil LP, reperforated a single hole in each row...but in a way that makes them line up.

I find identifying reperforations with certainty quite difficult (well, sometimes they are obvious), so I'm always glad for discussions like this.