Hi Tomx4

Firstly about the FDR collection sold by Harmer. FDR's estate sold his collection of covers and stamps through Harmer in large lots which were mostly purchased by stamp dealers. FDR's collection consisted mainly of common items, so Harmer applied the "from the FDR collection" notation to add value to what otherwise would be $1 box covers and penny stamps.
As to your cover, it's a great example of a philatelic cover. The fractional currency is used so far out of date that it can only be disregarded (are there reprints of these items?). What you're left with is a registered flight cover (possibly with missing stamps bottom right of top scan) signed by captain and crew. I would guestimate that the value is not more than $10-20.
However, I'm thinking that perhaps the fractional currency soaked off the cover might be worth more than the cover as it now stands. Or does the out of date cancel kill the value? Perhaps someone with knowledge of these issues can advise.