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are the "159 & 3" slugs askew on that postmark or is that just how it's supposed to be?
They are supposed to be there. Without looking it up, I think the "159" is the prefix of the ZIP Code for that area (i.e. 15901). Not sure about the "3" on the opposite side of the cancel, but I suspect it relates to the cancellation machine or clerk or office that was responsible for applying the cancellation.
Some others on SCF may be able to provide you with further information.